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There are a number of side effects with Mirena that you should report to your healthcare provider. These include but are not limited to:
- Signs of pelvic inflammatory disease (PID), such as:
- Prolonged or heavy vaginal bleeding
- Unusual vaginal discharge
- Lower abdominal pain (stomach pain)
- Pain during sex
- Fever and chills
- Severe pain within a few hours after insertion of Mirena (which could be a sign of a dangerous infection)
- New or worsening headaches, including migraines
- High blood pressure (hypertension)
- Depression
- Yellowing of the skin or the whites of your eyes (jaundice)
- Signs of an ectopic pregnancy (pregnancy outside the uterus), such as:
- Unusual vaginal bleeding
- Severe abdominal pain (stomach pain)
- Signs of an allergic reaction, including:
- An unexplained rash
- Hives
- Itching
- Unexplained swelling
- Wheezing
- Difficulty breathing or swallowing.
Let your healthcare provider know if, at any time, you cannot feel the removal threads of Mirena. This may signal that the device has been displaced and lost from the body, broken, or possibly perforated the uterus. Your healthcare provider can check the location of Mirena using an ultrasound or an x-ray.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD