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Mirena Warnings and Precautions

It's important to understand the precautions and warnings with Mirena before starting this intrauterine contraceptive. For example, Mirena may increase the risk of pelvic inflammatory disease (PID), a condition that can increase the risk of ectopic pregnancies and infertility. Other Mirena warnings and precautions also apply to women with certain health conditions (including liver disease, breast cancer, and diabetes).

Mirena: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Mirena® if you have:
  • A history of pelvic inflammatory disease (PID)
  • Had a serious pelvic infection
  • More than one current sexual partner (or if your partner has more than one sexual partner)
  • A weakened immune system due to HIV or AIDS, cancer, or IV drug abuse
  • Uterine cancer or cervical cancer
  • Unexplained vaginal bleeding
  • Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
  • Breast cancer (or a history of breast cancer)
  • Had an ectopic pregnancy (a "tubal" pregnancy) or are at high risk for an ectopic pregnancy
  • An intrauterine device (IUD) still in place
  • An abnormally shaped uterus or uterine fibroids
  • Diabetes
  • Had a blood clot or a clotting disorder
  • Heart disease or problems with your heart valves
  • Any allergies, including allergies to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you:
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding
  • Have recently had a baby.
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Last reviewed by: Kristi Monson, PharmD
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