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Nortrel Drug Interactions

Nortrel Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Nortrel is combined with any of the drugs listed above. If you are unsure about any particular interaction, it is a good idea to use a backup method of birth control until you can speak with your healthcare provider. It is important to understand that sometimes a backup method is recommended for quite a while (in some cases, an entire cycle). Your healthcare provider can give you more specific instructions about using a backup form of birth control.
Aminoglutethimide (Cytadren)
Taking Nortrel with aminoglutethimide may increase your risk of unintentional pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception (such as condoms).
Antibiotics
There have been reports of accidental pregnancy occurring in women taking birth control pills together with certain antibiotics. However, the significance of this interaction is still uncertain. Some antibiotics are more likely to cause problems than others. Any time you take an antibiotic, make sure to ask your healthcare provider if you need to use a backup method of contraception.
Aprepitant (Emend)
Aprepitant can make Nortrel less effective, perhaps increasing your chance of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception.
Barbiturates
Barbiturates may cause your body to metabolize the hormones in Nortrel too quickly, increasing your risk of pregnancy. Ask your healthcare provider if you should use a different method of contraception while taking a barbiturate.
Last reviewed by: Kristi Monson, PharmD
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