Modafinil (Provigil)
Modafinil may make
NuvaRing less effective, increasing your risk of pregnancy. Talk with your healthcare provider, as you may need to use a backup method of contraception.
Nafcillin (Nallpen, Unipen)
Nafcillin may cause your body to metabolize the hormones in NuvaRing too quickly, increasing your risk of pregnancy. Ask your healthcare provider if you should use a backup method of contraception.
Protease Inhibitors
Using NuvaRing together with a protease inhibitor may increase your risk of pregnancy or side effects. Talk with your healthcare provider before using NuvaRing with a protease inhibitor.
Rifamycin Antibiotics
Rifamycin antibiotics may make NuvaRing less effective, increasing your risk of pregnancy. Talk with your healthcare provider before taking these medications together, as you may need to use an alternate form of birth control.
Selegiline (Eldepryl, Emsam, Zelapar)
The hormones in NuvaRing may increase the level of
selegiline in your blood, increasing your risk of side effects. Your healthcare provider may need to lower your
selegiline dosage or may recommend an alternate form of contraception.
St. John's Wort
St. John's wort (a commonly used herbal supplement) may decrease the effectiveness of NuvaRing, increasing the chance of pregnancy. In general, you should not take St. John's wort while using NuvaRing.
Warfarin (Coumadin, Jantoven)
NuvaRing may make warfarin less effective. Additionally, warfarin is often used to treat blood clotting disorders, and NuvaRing is not recommended for women with such disorders (as it may increase the risk of blood clots).