NuvaRing Drug Interactions

When certain medications, such as barbiturates, protease inhibitors, or modafinil, are taken while you are using NuvaRing, drug interactions may occur. Not only can negative drug interactions reduce the effectiveness of NuvaRing and increase your risk of pregnancy, but you may also develop certain side effects. Other medicines that may lead to NuvaRing interactions include cyclosporine, rifamycin antibiotics, aprepitant, and certain seizure medications.

 

An Introduction to NuvaRing Drug Interactions

NuvaRing® (etonogestrel/ethinyl estradiol vaginal ring) can potentially interact with several other medicines. Some of these medicines that may lead to NuvaRing interactions include:
 
  • Aminoglutethimide (Cytadren®)
  • Aprepitant (Emend®)
  • Barbiturates, such as:

 

    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)

 

  • Certain seizure medications, such as:

 

 

  • Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
  • Griseofulvin (Grifulvin®)
  • Modafinil (Provigil®)
  • Nafcillin (Nallpen®, Unipen®)
  • Protease inhibitors, such as:

 

 

(NuvaRing Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;