Nystatin Powder

Nystatin is a prescription antifungal medicine that comes in many different forms and strengths. It is approved for the treatment of various fungal infections, such as thrush, yeast infections, and diaper rash.
The powder form of nystatin is used for treating fungal infections that occur on the surface of the body, such as yeast diaper rashes and fungal infection of the feet. Although ointments and creams can also be used to treat diaper rashes, a powder may be more appropriate for very moist areas.
Nystatin works by binding to ergosterol, an important component of the fungal cell membrane. This action changes the fungal cell membrane, making it more "leaky" and allowing for the leakage of important cellular contents to occur. Even when taken by mouth, nystatin is not significantly absorbed into the bloodstream (it stays in the digestive tract and is excreted through the feces).
(Click Nystatin for more information about the other forms of nystatin, to learn about the specific effects of this drug, and to find out what you should discuss with your healthcare provider before starting treatment.)
Last reviewed by: Kristi Monson, PharmD
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