Nystatin Warnings and Precautions

Before starting treatment for your fungal infection, it's important to be aware of the warnings and precautions for nystatin. For example, check with your healthcare provider before using the drug if you have kidney disease, are taking any other medications, or have any allergies. Warnings also include stopping treatment if you notice signs of an allergic reaction, and using extreme caution if you are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider Before Taking Nystatin?

You should talk with your healthcare provider prior to taking nystatin if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • Any other allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Nystatin Warnings and Precautions

Some warnings and precautions to be aware of with nystatin include the following:
  • For most people, taking nystatin (even by mouth) will not result in significant levels of nystatin in the blood. For this reason, the drug should be used only for fungal infections that can be treated directly. For instance, nystatin works well for treating skin or mouth fungal infections but is ineffective for treating bloodstream, brain, or urinary tract fungal infections.
  • If you have kidney disease, check with your healthcare provider before taking nystatin.
  • Although nystatin is very unlikely to cause significant side effects, stop using it and contact your healthcare provider if you think you may have an allergic reaction to nystatin. Signs of such a reaction might include:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling (especially of the lips, mouth, or throat)
    • Wheezing or other breathing problems.
  • Nystatin is considered a pregnancy Category C medication. This means that it might not be safe for use during pregnancy, although the full risks are not known. Talk to your healthcare provider about the risks and benefits of using nystatin during pregnancy (see Nystatin and Pregnancy for more information).
  • It is unknown if nystatin passes through breast milk. Therefore, if you are breastfeeding or plan to start, be sure to talk with your healthcare provider about using nystatin (see Nystatin and Breastfeeding for more information).

More Headlines in Nystatin Warnings and Precautions

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Last reviewed by: Kristi Monson, PharmD
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