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Drug Interactions With Ocella

Ocella Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Ocella is combined with any of the drugs listed above.
ACE Inhibitors and Angiotensin II Receptor Blockers (ARBs)
Combining Ocella with ACE inhibitors or ARBs can increase the risk of high potassium levels in your blood (hyperkalemia). Your healthcare provider should check your potassium levels regularly, particularly during the first cycle you use Ocella.
Aminoglutethimide (Cytadren)
Aminoglutethimide may make Ocella less effective, possibly increasing your risk of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception (such as condoms).
Antibiotics
There have been reports of accidental pregnancy occurring in women taking birth control pills and certain antibiotics. However, it is still uncertain how significant this interaction may be. It is known that rifampin (Rifadin®) and minocycline (Minocin®) can make Ocella less effective. Ask your healthcare provider if you need a backup method of contraception any time you take an antibiotic.
Aprepitant (Emend)
Aprepitant may make Ocella less effective, perhaps increasing your chance of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception.
Atorvastatin (Lipitor)
Atorvastatin may increase the level of Ocella in your blood, which may increase your risk of Ocella side effects. Check with your healthcare provider before taking these medications together.
Barbiturates
Barbiturates may cause your body to metabolize the hormones in Ocella too quickly, possibly increasing your risk of pregnancy. Ask your healthcare provider if you should use a different method of contraception while taking a barbiturate.
Last reviewed by: Kristi Monson, PharmD
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