OTC Oxybutynin Patch Side Effects

Possible Side Effects

OTC oxybutynin patch is the nonprescription version of Oxytrol®, which is available only by prescription. Most of the time, limited information is available on the possible side effects of nonprescription medications. However, because OTC oxybutynin patch and prescription Oxytrol are the same strength patches, it is assumed that their side effects will be quite similar.
Oxytrol has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people using the drug were documented and compared to those that occurred in another group of people using a placebo (a patch without any active ingredient). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group not using the medicine.
In these studies, the most common side effects of prescription Oxytrol included:
  • Itching at the patch application site -- in up to 16.8 percent of people
  • Dry mouth -- up to 9.6 percent (see Oxytrol and Dry Mouth)
  • Redness at the patch application site -- up to 8.3 percent
  • Constipation -- up to 3.3 percent
  • Rash at the patch application site -- up to 3.3 percent
  • Diarrhea -- up to 3.2 percent
  • Vision changes -- up to 2.5 percent
  • Painful urination -- up to 2.4 percent.

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any adverse reactions while using the drug or if something "just does not seem right." While it may not be an OTC oxybutynin patch side effect, your healthcare provider will be able to diagnose and treat the problem.
Last reviewed by: Kristi Monson, PharmD
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