Paroxetine Mesylate Capsules

Drug Interactions

Paroxetine mesylate capsules may react with a number of other medications (see Drug Interactions With Paroxetine Mesylate Capsules).

Are There Alternatives?

Paroxetine mesylate capsules are currently the only non-hormonal treatment approved for reducing hot flashes from menopause. Other medicines approved for the treatment of hot flashes contain the hormone estrogen alone or a combination of estrogen with progestin (see Hormone Replacement Therapy for information about hormonal treatment for hot flashes). Such medications may include but are not limited to:
In addition, several other non-hormonal medications, though not FDA-approved to treat hot flashes, are sometimes used "off-label" for this reason. Examples of these medications include:
  • Complementary and alternative treatments, such as black cohosh and soy.
Some women also find that a variety of coping strategies or lifestyle changes can help them get through hot flashes. Examples of some of the strategies you can try include:
  • Keeping track of when hot flashes occur, so you can identify and avoid things that trigger your hot flashes
  • Moving to a cool area when a hot flash starts
  • Sleeping with a fan on if hot flashes occur at night
  • Drinking a cool liquid when a hot flash starts
  • Losing weight (if you are overweight).
Last reviewed by: Kristi Monson, PharmD
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