Drug Interactions With Phendimetrazine (Cont.)

Phendimetrazine Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when phendimetrazine is combined with any of the drugs listed above.
 
Diabetes Medications
Because you may eat less while taking phendimetrazine (because the drug is an appetite suppressant), your healthcare provider may need to decrease the dose of your diabetes medications.
 
Monoamine Oxidase Inhibitors
Taking phendimetrazine and MAOIs together can cause life-threatening side effects, such as very high blood pressure. Do not take phendimetrazine if you have taken an MAOI within the past 14 days.
 
Sodium Bicarbonate
Sodium bicarbonate (when taken as a medication, not in normal food use) can increase the level of phendimetrazine in your blood, possibly increasing your risk of side effects of phendimetrazine. Check with your healthcare provider before taking these medications together.
 
Tricyclic Antidepressants
Taking phendimetrazine with a tricyclic antidepressant can increase the risk of dangerous side effects from either medication. Check with your healthcare provider before combining these two medications.
 
Tromethamine
Tromethamine can increase the level of phendimetrazine in your blood, possibly increasing the risk of side effects. Talk with your healthcare provider before taking these medications together.
 

Final Thoughts on Drug Interactions With Phendimetrazine

It is possible that not all drug interactions with phendimetrazine were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific drug interactions that may apply to you.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;