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Precautions and Warnings With Phendimetrazine

It's important to be aware of certain precautions and warnings with phendimetrazine prior to taking it. For example, you should be aware of the drug's habit-forming qualities and the risk of addiction. Other precautions and warnings with phendimetrazine concern its potential to impair your ability to drive a car, operate machinery, or perform other tasks that require complete concentration.

Phendimetrazine: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking phendimetrazine tartrate (Bontril®) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also be sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Phendimetrazine

Warnings and precautions to be aware of prior to taking phendimetrazine include the following:
  • The medication can increase your heart rate and blood pressure. This can cause problems, especially if you already have high blood pressure or heart problems.
  • Phendimetrazine is chemically similar to amphetamines, which are often abused. Taking phendimetrazine for a long time can lead to dependence. Because phendimetrazine is often abused, there are special rules for prescribing and dispensing it.
  • The medication can make glaucoma worse. Check with your healthcare provider before taking phendimetrazine if you have this condition.
  • If you have diabetes and take insulin, your healthcare provider may need to adjust your insulin dosage, as phendimetrazine suppresses the appetite.
  • Before you take phendimetrazine, your healthcare provider should make sure that your obesity is not caused by a medical problem.
  • Phendimetrazine may affect your ability to perform tasks that require complete concentration, such as driving, operating machinery, or piloting an airplane, especially during the first few weeks of treatment. You should use caution when performing these activities until you know exactly how the drug affects you.
  • Phendimetrazine can interact with a number of different medications (see Drug Interactions With Phendimetrazine).
  • Phendimetrazine may not be safe for use during pregnancy (see Bontril and Pregnancy).
  • It is not known if phendimetrazine passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Bontril and Breastfeeding).
Last reviewed by: Kristi Monson, PharmD
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