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Side Effects of Polidocanol

Injection site reactions, like bruising, irritation, and discoloration, are among the most commonly reported side effects of polidocanol. Such reactions are typically mild and easily treated. However, there are some more serious side effects to watch out for, such as an allergic reaction, signs of a stroke, or signs of a blood clot in the leg.

An Introduction to Polidocanol Side Effects

Just like any medicine, polidocanol (Asclera™) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with polidocanol. Your healthcare provider can discuss a more complete list with you.)

Serious Side Effects

Some polidocanol side effects can be quite serious. Be sure to report any of the following potentially dangerous reactions to your healthcare provider:
  • Signs or symptoms of a severe allergic reaction, such as:
    • Hives or a rash (especially a widespread rash)
    • Widespread itching
    • Swelling
    • Wheezing or difficulty breathing
  • Severe pain (which usually occurs if polidocanol leaks outside a vein)
  • Severe skin or tissue damage (which usually occurs if polidocanol is accidentally injected into an artery or if it leaks outside a vein)
  • Signs of a stroke, such as:
    • Vision or speech changes
    • Weakness or numbness in an arm or leg
    • Severe headache
  • Signs of a blood clot in the leg, such as:
    • Pain in the calf
    • Leg cramps
    • Leg or foot swelling
  • Signs of a blood clot in the lung, such as:
    • Shortness of breath
    • Sharp chest pain
    • Coughing up blood.

More Headlines in Side Effects of Polidocanol

‣ Reported Side Effects
‣ Final Thoughts
Last reviewed by: Kristi Monson, PharmD
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