Premature Ovarian Failure

Cause of Premature Ovarian Failure

Although researchers have a general idea of what causes premature ovarian failure, in most cases, the exact cause remains unclear.

Statistics on Premature Ovarian Failure

Premature ovarian failure affects approximately:
  • One in 10,000 women by age 20
  • One in 1,000 women by age 30
  • One in 250 women by age 35
  • One in 100 women by age 40.

Common Treatments for Premature Ovarian Failure

Doctors often prescribe hormone replacement therapy (also known as HRT) to relieve some of the symptoms of POF. However, there currently is no treatment that is proven safe and effective in restoring normal function of the ovaries or in improving fertility.

Premature Ovarian Failure and Pregnancy

It is difficult for women with POF to become pregnant because their ovaries are not functioning properly. However, between 5 and 10 percent of women with the condition become pregnant without treatment.
Last reviewed by: Arthur Schoenstadt, MD
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