Proquin XR and Tendon Rupture

Who Is at Risk?

Tendon rupture can occur in anyone who takes Proquin XR. However, some people appear to have a higher risk. This includes people who:
  • Are over 60 years of age
  • Take corticosteroid medications (see Proquin XR Drug Interactions)
  • Have had a kidney, heart, or lung transplant
  • Engage in strenuous physical activity
  • Have kidney failure (renal failure)
  • Have a history of tendon problems, such as rheumatoid arthritis.

Signs of Tendon Problems With Proquin XR

If you are taking Proquin XR or any other quinolone, watch for any signs of tendonitis or tendon rupture, including:
  • Tendon pain, swelling, or inflammation
  • A snapping or popping sound, followed by sharp pain in a tendon area
  • Immediate bruising after an injury to a tendon area
  • Weakness
  • Difficulty moving your joints or walking.
It should be noted that tendon problems could even occur several months after treatment has stopped.

Talking to Your Healthcare Provider

Talk to your healthcare provider about Proquin XR and tendon problems before you begin treatment, especially if you have any of the risks listed in this article. If you develop signs of tendon problems or experience a ruptured tendon while taking Proquin XR, stop taking it and contact your healthcare provider immediately. Do not exercise or use the affected area until your healthcare provider makes sure you do not have a ruptured tendon.
Last reviewed by: Kristi Monson, PharmD
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