Proquin XR Uses

How Does Proquin XR Work?

Proquin XR works by killing certain bacteria that cause infections. It does this by interfering with two bacterial enzymes called topoisomerase IV and DNA gyrase. These enzymes are needed by the bacteria to copy and repair DNA, important steps required for the bacteria to multiply.

Can Children Use It?

Proquin XR is not approved for children under the age of 18, as it has not been adequately studied in this age group. Like other quinolones, Proquin XR may cause bone, joint, or tendon problems in children.

Can Older Adults Use It?

Proquin XR can be used in older adults. However, most of the drug is removed from the body by the kidneys. Because older adults, in general, are more likely to have reduced kidney function, they may be at greater risk for Proquin XR side effects. In addition, older adults using this drug have a higher risk for QT prolongation (a problem with the heart rhythm) and tendon problems (see Proquin XR and Tendon Rupture).

Is Proquin XR Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend this product for something other than urinary tract infections. This would be known as an "off-label" use. Proquin XR may be used off-label to treat other infections caused by bacteria that are susceptible to the medication.
Last reviewed by: Kristi Monson, PharmD
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