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Proquin XR

If you have cystitis, your healthcare provider may recommend an antibiotic called Proquin XR. This medication kills the infection-causing bacteria by interfering with two enzymes they use in order to multiply. It comes in tablet form and is usually taken once daily for three days. Commonly reported side effects include yeast infection, headache, and throat inflammation.

What Is Proquin XR?

Proquin® XR (ciprofloxacin hydrochloride) is a prescription antibiotic medication. It belongs to a group of medications called fluoroquinolones, or "quinolones" for short. Proquin XR is approved to treat a type of urinary tract infection called cystitis (commonly known as a bladder infection).
(Click Proquin XR Uses for more information on this topic, including possible off-label uses.)

Who Makes Proquin XR?

Proquin XR is made by Depomed, Inc.

How Does It Work?

Proquin XR works by killing certain bacteria that can cause infections. It does this by interfering with two enzymes in the bacteria: topoisomerase IV and DNA gyrase. These enzymes are necessary for the bacteria to copy and repair DNA, which are critical steps needed for the bacteria to multiply.

Clinical Effects

Proquin XR was shown to treat bladder infections (cystitis) as well as Cipro® (ciprofloxacin) in a clinical study. In this study, one group of people with bladder infections was given Proquin XR while another group was given Cipro. Up to 95 percent of people given Proquin XR were free of the bacteria causing their infection after three days, compared with up to 91 percent of people given Cipro.
Last reviewed by: Kristi Monson, PharmD
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