Prostin E2 Warnings and Precautions

Specific Precautions and Warnings With Prostin E2

Some warnings and precautions to be aware of prior to using this medication include the following:
  • Prostin E2 should only be given by a trained healthcare provider in a hospital setting that can provide intensive care and emergency surgery if needed.
  • This medication should not be used if the fetus is able to live outside of the womb.
  • If Prostin E2 does not cause a complete abortion, other treatment may be needed to ensure all the products of conception leave the body. Otherwise, serious problems may occur, such as infection or bleeding.
  • Certain women may need to be monitored more closely when using this medicine, including those who have any of the following conditions:
  • You may experience a temporary fever while receiving this medication, usually 15 to 45 minutes after the suppository is inserted. Drinking fluids may help reduce the fever. Your temperature should return to normal within two to six hours after treatment ends. Contact your healthcare provider if your fever persists, however, as it could be a sign of a more serious problem.
  • Prostin E2 is a pregnancy Category C medication, which means it may not be safe for use during pregnancy (see Prostin E2 and Pregnancy), although obviously it is intended for use only in women who are pregnant or were previously pregnant.
  • It is unknown whether Prostin E2 passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to receiving the drug (see Prostin E2 and Breastfeeding).
Last reviewed by: Kristi Monson, PharmD
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