Provera and Ovulation

Available by prescription only, Provera® (medroxyprogesterone acetate) is a medicine approved to treat irregular vaginal bleeding and restore menstruation in premenopausal women who have not been having regular periods. It is also used to help prevent cancer of the uterus in postmenopausal women who are using estrogen hormone therapy.
Provera contains medroxyprogesterone, a synthetic progestin hormone. Unlike injectable forms of medroxyprogesterone that are approved to prevent pregnancy, Provera does not prevent ovulation (release of an egg from the ovary) when used at recommended doses.
(Click Provera Uses for more information on specific uses for this medicine, including possible off-label reasons a healthcare provider may recommend this drug. This article also takes an in-depth look at how Provera works.)
Last reviewed by: Kristi Monson, PharmD
Pregnancy and Pain