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Provera Drug Interactions

Provera Drug Interactions Explained

The following sections explain in detail the potentially negative reactions that can occur when Provera is combined with any of the drugs listed above.
Cyclosporine
Provera may increase the level of cyclosporine in your blood, potentially increasing your risk for side effects. If you take these medications together, your healthcare provider may choose to monitor you more closely and give you a lower cyclosporine dosage.
CYP 3A4 Inducer Medications
The liver breaks down the hormones in Provera using enzymes known as CYP 3A4 enzymes. Medications known as CYP 3A4 inducers can increase the activity of these enzymes. Thus, combining Provera with one of these drugs may decrease the level of Provera in your body, possibly making it less effective.
Thyroid Medications
If you take medications for an underactive thyroid (hypothyroidism), your healthcare provider may need to increase your dose after you start taking Provera. Your healthcare provider will monitor you and adjust the dose of your thyroid treatment if needed.

Final Thoughts

It is possible that not all drug interactions with Provera were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.

More Headlines in Provera Drug Interactions

↶ An Overview of Interactions With Provera
Last reviewed by: Kristi Monson, PharmD
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