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Provera Side Effects

Serious Side Effects

Some side effects of Provera are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
    • Vision or speech changes
    • Weakness or numbness in an arm or leg
    • Severe headache
  • Signs of a blood clot in the lung, such as:
    • Shortness of breath
    • Sudden chest pain
    • Coughing up blood
  • Signs of a blood clot in the leg, such as severe pain or swelling of the calf
  • Yellowing of the whites of the eyes or skin (jaundice)
  • Chest pain or heaviness, which could be signs of a heart attack
  • Persistent abnormal menstrual periods or unusual or heavy vaginal bleeding
  • High blood glucose levels
  • Breast lumps
  • High blood pressure (hypertension)
  • Signs of an allergic reaction, such as:
    • Hives
    • Itching
    • Unexplained swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing or swallowing.

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking Provera or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
Last reviewed by: Kristi Monson, PharmD
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