What Is Provera?

If you have amenorrhea (absence of a menstrual period) or abnormal vaginal bleeding, you may benefit from Provera® (medroxyprogesterone acetate). But what is Provera and how does it work?
Provera contains a synthetic form of a female progestin hormone. This prescription medication works by replacing progesterone when the body is unable to make enough.
This drug comes in tablet form and is taken for several days. Three to seven days after treatment is stopped, vaginal bleeding occurs. This can help to restore regular periods in women who have been having irregular periods or no periods at all.
Provera is also approved for use in combination with estrogen to help prevent a thickening of the uterine lining in postmenopausal women. By preventing this overgrowth of the uterine lining, the drug can help decrease the risk for uterine cancer.
(Click Provera for more details on what this medicine is and how it works. This full-length article also discusses potential side effects, general dosing guidelines, possible safety concerns, and more.)
Last reviewed by: Kristi Monson, PharmD
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