Seasonale Drug Interactions

Antibiotics, barbiturates, and certain seizure medications are among the drugs that may negatively interact with Seasonale. Drug interactions such as these can alter the amount of medications in your blood, possibly increasing your risk of pregnancy or certain side effects. To avoid Seasonale drug interactions, tell your healthcare provider about all other medications you are currently taking, including vitamins and herbal supplements.

An Introduction to Seasonale Drug Interactions

Seasonale® (levonorgestrel/ethinyl estradiol) can potentially interact with numerous other medicines. Some of the medicines that may lead to Seasonale drug interactions include:
  • Aminoglutethimide (Cytadren®)
  • Antibiotics
  • Aprepitant (Emend®)
  • Atorvastatin (Lipitor®) or combination medications that contain atorvastatin (Caduet®, Liptruzet™)
  • Barbiturate medications, such as:
    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)
Last reviewed by: Kristi Monson, PharmD
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