Drug Interactions With Sibutramine

Drug interactions with sibutramine are possible if it is taken with certain other medications, such as some pain medications; cough cold, or allergy medications; and other weight-loss medications. Some of these drug interactions with sibutramine can affect the level of medications in your blood, possibly increasing your risk of side effects or decreasing the effectiveness of the medications. To avoid these interactions, tell your healthcare provider about any other medications you are taking prior to starting sibutramine.

 

An Introduction to Drug Interactions With Sibutramine

Sibutramine hydrochloride monohydrate (Meridia®) can potentially interact with a few other medicines. Some of these medicines that may lead to sibutramine interactions include:
 
  • Certain antibiotics or antifungal medications
  • Certain pain medications, including:

 

    • Fentanyl (Actiq®, Duragesic®, Fentora™, Sublimaze®)
    • Meperidine (Demerol®)
    • Pentazocine (Talwin®)
    • Tramadol (Ultram®, Ultracet®) 

 

  • Cough, cold, or allergy medications
  • Ergot medications, such as:

 

    • Bromocriptine (Parlodel®)
    • Dihydroergotamine (Migranal®)
    • Ergonovine
    • Ergotamine (Bellamine S, Cafergot®, Ergomar®)
    • Methylergonovine (Methergine®)
    • Pergolide (Permax®) 

 

 

 

 

 

 

 

 

 

(Drug Interactions With Sibutramine Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;