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Drug Interactions With Sprintec

Many medicines could potentially cause negative drug interactions with Sprintec, including seizure medications, antibiotics, protease inhibitors, and aminoglutethimide. Taking the birth control pill in combination with these drugs can increase your risk of pregnancy or side effects. If you are ever unsure of what to do about a Sprintec drug interaction, use backup birth control until you can speak with your healthcare provider.

An Introduction to Sprintec Drug Interactions

Sprintec® (norgestimate/ethinyl estradiol) is a prescription oral contraceptive that is a generic version of Ortho-Cyclen®. It can potentially interact with several other medicines. Most women have heard stories about accidental pregnancies occurring due to interactions between birth control pills and antibiotics, but antibiotics are not the only medications that interact with birth control pills. If you are ever unsure about what to do about a Sprintec drug interaction, be sure to use backup birth control until you can speak with your healthcare provider. Some of the medicines that may lead to Sprintec interactions include:
  • Aminoglutethimide (Cytadren®)
  • Antibiotics
  • Aprepitant (Emend®)
  • Atorvastatin (Lipitor®) or combination medications that contain atorvastatin (Caduet®, Liptruzet™)
  • Barbiturate medications, including (but not limited to):
    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)
Last reviewed by: Kristi Monson, PharmD
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