Macrodantin Antibiotic Information

A prescription antibiotic, Macrodantin® (nitrofurantoin macrocrystalline) is a medicine that can help prevent and treat urinary tract infections (UTIs). It comes in the form of a capsule and is typically taken four times a day. For long-term prevention of UTIs, it may be taken just once a day. Most people tolerate this drug well, but side effects can include vomiting, nausea, and loss of appetite.
Before starting treatment with Macrodantin, it's important to discuss the antibiotic's safety information with your healthcare provider. For example, tell your healthcare provider if you have:
  • Anemia
  • Kidney disease, such as kidney failure (renal failure)
  • Diabetes
  • Glucose-6-phosphate dehydrogenase deficiency
  • Vitamin B deficiency
  • An electrolyte imbalance
  • Any allergies, including to food, dyes, or preservatives.
(For more information on this antibiotic, click Macrodantin. This article takes an in-depth look at how it works, when and how to take it, what to do if you miss a dose, and more.)
Last reviewed by: Arthur Schoenstadt, MD