Prostin E2 Medication Information

By affecting the cervix and causing uterine contractions, Prostin E2® (dinoprostone vaginal suppository) can terminate a pregnancy, empty the contents of the uterus, or treat a certain cancer-like condition called gestational trophoblastic disease. It comes as a suppository that is inserted high in the vagina by a healthcare provider in a hospital setting.
Although this drug is quite effective for many women, not everyone can receive this medication. Information on Prostin E2 should be discussed with your healthcare provider before starting treatment to minimize risks and to help ensure a safe procedure. For example, you may not be able to receive this suppository if you have had a recent heart attack or if you have lung disease.
Although most women tolerate this medication well, side effects are possible and can include fever, vomiting, and diarrhea. In most cases, however, reactions to the drug tend to be mild and easy to treat.
(Click Prostin E2 for more information, including a detailed description of the medicine's effects, a list of potential side effects that may occur, and dosing tips on when and how this medication is administered.)
Last reviewed by: Arthur Schoenstadt, MD