Yasmin and Pregnancy

In animal studies on Yasmin and pregnancy, one of the hormones in the drug increased the risk of miscarriages and slow fetal development. As a result, the FDA has classified Yasmin as a pregnancy Category X medication, which means it should be avoided during pregnancy. If you are taking Yasmin and pregnancy occurs, stop using the contraceptive right away.

Yasmin and Pregnancy: An Overview

Yasmin® (drospirenone/ethinyl estradiol) is a prescription birth control pill, also known as an oral contraceptive. As with all oral contraceptives, Yasmin should not intentionally be used during pregnancy.
(Ocella™, Syeda™, and Zarah™ birth control pills are generic versions of Yasmin. The information in this article applies to Ocella, Syeda, and Zarah as well.)

Yasmin and Pregnancy Category X

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category X is given to medications that should not be used during pregnancy, usually due to the serious problems that could potentially occur, such as birth defects or miscarriages.
Even though Yasmin is a pregnancy Category X medication, it is not likely to cause any problems if accidentally used during early pregnancy. When the drug was studied in humans, 14 women accidentally became pregnant while taking Yasmin. One of these babies was born with a problem of the esophagus, although it is not clear if this was related to Yasmin.
In animal studies, drospirenone (one of the hormones in Yasmin) increased the risk of miscarriages and slow fetal development. When Yasmin was given to animals in late pregnancy, male offspring developed feminine characteristics, probably because the drug works against testosterone and other male hormones. However, it is not known if these problems will also occur in humans.

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Last reviewed by: Kristi Monson, PharmD
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