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Yaz and Antibiotics

Yaz® (drospirenone/ethinyl estradiol) is a prescription oral contraceptive for women. It is primarily used to prevent pregnancy but can also be used to treat symptoms of PMDD (premenstrual dysphoric disorder) and acne.
There is a possible drug interaction between antibiotics and Yaz. There have been reports of accidental pregnancy occurring in women taking birth control pills (such as Yaz) and certain antibiotics. However, the significance of this interaction is still uncertain.
It is known that rifampin (Rifadin®) and minocycline (Minocin®) can make Yaz less effective. Ask your healthcare provider if you need a backup method of contraception while you are taking an antibiotic.
(Click Yaz Drug Interactions for more information about the potential drug interaction between certain antibiotics and Yaz, to find out what other medications may interact with the birth control pill, and to learn about the effects of these other interactions.)
Last reviewed by: Kristi Monson, PharmD
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