People who have specific types of varicose veins -- namely, reticular veins and spider veins -- may see improvement in their condition by using polidocanol. The medication is injected into the affected veins, where it damages the inner lining. Eventually, the vein is replaced by scar tissue and disappears. Side effects can include various reactions at the injection site, although it is generally well tolerated.

What Is Polidocanol?

Polidocanol (Asclera™) is a prescription medication. It is used to treat spider veins and reticular veins (two common types of varicose veins). It is injected directly into the affected veins.
(Click What Is Polidocanol Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, polidocanol can cause side effects. However, not everyone who uses the drug will experience problems. Most people tolerate it quite well.
If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious reactions are less common.
Possible polidocanol side effects include but are not limited to:
  • Bruising
  • Irritation
  • Discoloration
  • Pain.
(Click Side Effects of Polidocanol to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Last reviewed by: Kristi Monson, PharmD
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